Serveur d'exploration sur la maladie de Parkinson

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Restless legs syndrome in Parkinson's disease

Identifieur interne : 000968 ( Main/Exploration ); précédent : 000967; suivant : 000969

Restless legs syndrome in Parkinson's disease

Auteurs : Cecilia M. Peralta [Autriche, Argentine] ; Birgit Frauscher [Autriche] ; Klaus Seppi [Autriche] ; Elisabeth Wolf [Autriche] ; Gregor K. Wenning [Autriche] ; Birgit Högl [Autriche] ; Werner Poewe [Autriche]

Source :

RBID : ISTEX:9D671D956B2BCC62DCF4088EE5320A8CB8AA80CA

English descriptors

Abstract

We aimed to investigate the prevalence of restless legs syndrome (RLS) according to essential diagnostic criteria, and to explore potential associations with clinical features, especially motor fluctuations, in a cohort of 113 patients with idiopathic Parkinson's disease (PD). Twenty‐eight (24%) fulfilled essential diagnostic criteria for RLS. They were younger (63.1 ± 8.6 vs. 68.8 ± 9.0 years; P = 0.004), had an earlier onset of PD (54.1 ± 9.5 vs. 59.2 ± 10.3 years; P = 0.018), and received lower levodopa equivalent doses (578.4 ± 382.2 vs. 779.1 ± 459.6 mg/day; P = 0.04) than patients with PD who scored negative for RLS. In 23 patients (82%), RLS symptom onset was after PD onset (mean interval, 4.5 ± 3.7 years). The majority (n = 17, 61%) who scored positive for RLS reported that the urge to move the legs and unpleasant sensations were associated with wearing off, raising the possibility of RLS mimics in fluctuating patients with PD. © 2009 Movement Disorder Society

Url:
DOI: 10.1002/mds.22694


Affiliations:


Links toward previous steps (curation, corpus...)


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